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ITCC is partner in many projects that are contributing at different levels to improve access to innovative treatments for the paediatric and adolescent populations and enabling all key stakeholders in paediatric oncology to cooperate in a combined effort towards the goals of advancing treatments for childhood/AYA cancers.
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ITCC Current Projects ITCC Completed Projects

ITCC Current Projects

VAGABOND

VAGABOND

Validation of Actionable (epi) Genomic Aberrations in a paediatric Oncology Network for Doctorate Students
A European paediatric oncology doctoral training network focusing on 15 cutting-edge research projects studying molecular, epigenetic and immunological targets. All projects (partly) include target identification, in vitro and in vivo validation, compound testing and preparation for clinical implementation.
H2020-MSCA-ITN-2020 - Coordinator: Prof. Dr. Jan Molenaar, PMC

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ALADDIN

ALADDIN

Multi-stakeholder Education Alliance to Accelerate Drug Development for Children and Adolescent with Cancer
An educational program on strategic and regulatory science in paediatric oncology drug development to foster expertise and strengthen true multi-stakeholder collaboration.  
ERASMUS-EDU-2021-PI-ALL-INNO - Coordinator: ACCELERATE

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UNICA4EU

UNICA4EU

Towards an UNIque approach for artificial intelligence data-driven solutions to fight Childhood cAncer FOR Europe
The objective is to map the current landscape of Artificial Intelligence (AI) applications for Childhood Cancer to understand how AI can help improve care pathways in the EU.
PPPA-2021-AIPC - Coordinator: Prof. Pamela Kearns, SIOP Europe
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BRCAddict

BRCAddict

Harnessing BRCAness as a therapeutic target in high-risk pediatric solid tumors
TRANSCAN-2 - Coordinator: Stefan Pfister, DKFZ/KiTZ
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ITCC Completed Projects

ITCC-P4

ITCC-P4

A comprehensive ‘paediatric preclinical POC platform’ to enable clinical molecule development for children with cancer.

ITCC-P4 is a comprehensive ‘paediatric preclinical POC platform’ to enable clinical molecule development for children with cancer; ITCC-P4 project was initially launched to develop patient-specific preclinical laboratory models for the most common high-risk childhood cancers and also relapses that are currently under-treated. It was a formed public-private partnership supported by the European consortium ‘Innovative Medicines Initiative’ (IMI).

At the end of the project ITCC-P4, a non-for-profit commercial enterprise has been incorporated.

  • ITCC-P4 within IMI2 - IMI2-2015-07-05
  • Coordinator: DKFZ
  • End: Dec. 2023
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ACCESS within the JARC (Joint Action on Rare Cancers) scientific programme in Europe

ACCESS within the JARC (Joint Action on Rare Cancers) scientific programme in Europe

The objective of the JARC was to address the lack of systematic inclusion of rare cancers – including paediatric malignancies – in national cancer plans across Europe and help ensure the appropriate roll out and implementation of the European Reference Networks (ERNs).

  • Coordinator: Fondazione IRCCS Istituto Nazionale dei Tumori
  • End: Oct. 2019
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KidsCancer Kinome within 6e PCRD

KidsCancer Kinome within 6e PCRD

Selecting and validating drug targets from the human kinome for high risk paediatric cancers

KidsCancer Kinome made a comprehensive analysis of the human protein kinase family.

  • Coordinator: Institut Gustave Roussy
  • End: Apr. 2010
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